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For challenging hernia repair, choose AlloDerm® Regenerative Tissue Matrix
AlloDerm® Tissue Matrix is derived from cadaveric dermis and undergoes non-damaging proprietary processing that removes cells. AlloDerm® Tissue Matrix provides a strong and safe hernia repair and may minimize the risk of short- and long-term complications.1,2,3 AlloDerm® Tissue Matrix may keep patients from undergoing additional surgical interventions.
Supports rapid revascularization which can minimize the risk of infection4,5,6,7,8- Rapid revascularization through existing vascular channels and new blood vessel formation
- Rapid revascularization allows white blood cells to migrate to the site
Photo of AlloDerm® Tissue Matrix in a human patient. Bleeding AlloDerm® Tissue Matrix four weeks postimplantation.  |
Resists adhesion formations to bowel4,9- Minimizes complications such as bowel obstructions and fistula formations
- Allows for simpler future surgeries in the abdominal area
Photo Left: Polypropylene mesh in a guinea pig model without AlloDerm® Tissue Matrix present.
Photo Right: Polypropylene mesh with AlloDerm® Tissue Matrix as an adhesion barrier in a guinea pig model.  |
Allows local treatment in the setting of infection or exposure8,10- Intervene without removing the implant in most cases
- Minimizes likelihood of additional procedures and the resulting soft tissue loss
Photos of exposed AlloDerm® Tissue Matrix in a human patient taken at different time intervals monitor wound progression. Wound closed over the course of 3 months.  |
- Silverman RP et al. Ventral hernia repair using allogenic acellular dermal matrix in a swine model. Hernia. 2004;8:336-342.
- Holton LH 3rd et al. Human acellular dermal matrix for repair of abdominal wall defects: review of clinical experience and experimental data. LongTerm EffMed Implants. 2005; 15(5): 547-558.
- Buinewicz B, Rosen B. Acellular cadaveric dermis (AlloDerm™®): a new alternative for abdominal hernia repair. Ann Plast Surg. 2004 Feb;52(2):188-194.
- Menon NG et al. Revascularization of human acellular dermis in full-thickness abdominal wall reconstruction in the rabbit model. Ann Plast Surg. 2003 May;50(5):523-527.
- Diaz JJ Jr et al. Acellular dermal allograft for ventral hernia repair in the compromised surgical field. Am Surg. 2006 Dec;72(12):1181-1188.
- Kim H et al. Acellular dermal matrix in the management of high-risk abdominal wall defects. Am J Surg. 2006 Dec; 192(6):705-709.
- Patton JH Jr et al. Use of human acellular dermal matrix in complex and contaminated abdominal wall reconstructions. Am J Surg. 2007 Mar;193(3):360-363; discussion 363.
- Butler CE et al. Pelvic, abdominal, and chest wall reconstruction with AlloDerm® in patients at increased risk for mesh-related complications. Plast Reconstr Surg. 2005 Oct;116(5): 1263-1275; discussion 1276-1277.
- Kish KJ et al. Acellular dermal matrix (AlloDerm®): new material in the repair of stoma site hernias. Am Surg. 2005 Dec;71(12):1047-1050.
- Butler CE, Prieto VG. Reduction of adhesions with composite AlloDerm®/polypropylene mesh implants for abdominal wall reconstruction. Plast Reconstr Surg. 2004 Aug;114(2):464-473.
Before use, physicians should review all risk information and essential prescribing information which can be found in the AlloDerm® Regenerative Tissue Matrix Instructions for Use. Physicians should also refer to the Instructions for Use for detailed preparation and implantation instructions. |
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